Populations

Geography

EPAR Technical Report #346
Assessing Pharma’s Constraints, Opportunities, and Investment Options in Global Health R&D: An Analysis of SEC 10-K Filings
Publication Date: 04/23/2018
Type: Literature Review
Abstract

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

Executive Summary, Full Report
EPAR Research Brief #360
Economic Growth and Poverty in Ethiopia
Publication Date: 02/05/2018
Type: Research Brief
Abstract

In this brief, we report on measures of economic growth, poverty and agricultural activity in Ethiopia. For each category of measure, we first describe different measurement approaches and present available time series data on selected indicators. We then use data from the sources listed below to discuss associations within and between these categories between 1994 and 2017. 

Research Brief
EPAR Research Brief #242
Marketable Surplus Background
Publication Date: 01/08/2014
Type: Data Analysis
Abstract

The purpose of this analysis is to provide a measure of marketable surplus of maize in Tanzania. We proxy marketable surplus with national-level estimates of total maize sold, presumably the surplus for maize producing and consuming households. We also provide national level estimates of total maize produced and estimate “average prices” for Tanzania which allows this quantity to be expressed as an estimate of the value of marketable surplus. The analysis uses the Tanzanian National Panel Survey (TNPS) LSMS – ISA which is a nationally representative panel survey, for the years 2008/2009 and 2010/2011. A spreadsheet provides our estimates for different subsets of the sample and using different approaches to data cleaning and weighting. The total number of households for Tanzania was estimated with linear extrapolation based on the Tanzanian National Bureau of Statistics for the years 2002 and 2012. The weighted proportions of maize-producing and maize-selling households were multiplied to the national estimate of total households. This estimate of total Tanzanian maize-selling and maize-producing households was then multiplied by the average amount sold and by the average amount produced respectively to obtain national level estimates of total maize sold and total maize produced in 2009 and 2011.

Full Brief, Results Coding