Research Topics

EPAR Technical Report #346
Publication Date: 04/23/2018
Type: Literature Review
Abstract

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

EPAR Research Brief #257
Publication Date: 12/17/2013
Type: Data Analysis
Abstract

The FAO defines a farming system as “a population of individual farm systems that have broadly similar resource bases, enterprise patterns, household livelihoods and constraints, and for which similar development strategies and interventions would be appropriate. Depending on the scale of the analysis, a farming system can encompass a few dozen or many millions of households.” We use the farming systems as defined by the Food and Agriculture Organization (FAO) for Sub-Saharan Africa. The FAO identifies eight main farming systems in Tanzania 1) maize mixed, 2) root crop, 3) coastal artisanal fishing, 4) highland perennial, 5) agro-pastoral millet/sorghum, 6) tree crop, 7) highland temperate mixed, and 8) pastoral. This analysis uses data from the Tanzanian National Panel Survey (TZNPS) LSMS – ISA to provide a comparison of farming systems throughout Tanzania. The TZNPS is a nationally-representative panel survey that includes households from seven of the eight FAO farming systems with only the smallest farming system, pastoral, lacking any representation.

EPAR Research Brief #225
Publication Date: 10/15/2013
Type: Literature Review
Abstract

After cereals, root and tuber crops - including sweetpotato and yam (in addition to cassava and aroids), are the second most cultivated crops in tropical countries. This literature review examines the environmental constraints to, and impacts of, sweetpotato and yam production systems in Sub-Saharan Africa (SSA) and South Asia (SA). The review highlights crop-environment interactions at three stages of the sweetpotato/yam value chain: pre-production (e.g., land clearing), production (e.g., soil, water, and input use), and post-production (e.g., waste disposal, crop storage and transport). We find that sweetpotato and yam face similar environmental stressors. In particular, because sweetpotato and yam are vegetatively propagated, the most significant (and avoidable) environmental constraints to crop yields include disease and pest infection transmitted through the use of contaminated planting materials. Published estimates suggest yield gains in the range of 30–60% can be obtained through using healthy planting material. Moreover, reducing pest damage in the field can greatly increase the storage life of root and tuber crops after harvest – currently losses from rot and desiccation can claim up to 100% of stored sweetpotato and yam on smallholder farms.

EPAR Research Brief #215
Publication Date: 08/31/2013
Type: Literature Review
Abstract

Maize has expanded through the 20th and into the 21st century to become the principle staple food crop produced and consumed by smallholder farm households in Sub-Saharan Africa (SSA), and maize production has also expanded in South Asia (SA) farming systems. In this brief we examine the environmental constraints to, and impacts of, smallholder maize production systems in SSA and SA, noting where findings apply to only one of these regions. We highlight crop-environment interactions at three stages of the maize value chain: pre-production (e.g., land clearing), production (e.g., fertilizer, water, and other input use), and post-production (e.g., waste disposal and crop storage). At each stage we emphasize environmental constraints on maize production (such as poor soil quality, water scarcity, or crop pests) and also environmental impacts of maize production (such as soil erosion, water depletion, or chemical contamination). We then highlight best or good practices for overcoming environmental constraints and minimizing environmental impacts in smallholder maize production systems. Evidence on environmental constraints and impacts in smallholder maize production is uneven. Many environmental concerns such as biodiversity loss are commonly demonstrated more broadly for the agroecology or farming systems in which maize is grown, rather than specifically for the maize crop. And more research is available on the environmental impacts of agrochemical-based intensive cereal farming in Asia (where high-input maize is a common component) than on the low-input subsistence-scale maize cultivation more typical of SSA. Decisive constraint and impact estimates are further complicated by the fact that many crop-environment interactions in maize and other crops are a matter of both cause and effect (e.g., poor soils decrease maize yields, while repeated maize harvests degrade soils). Fully understanding maize-environment interactions thus requires recognizing instances where shortterm adaptations to environmental constraints might be exacerbating other medium- or long-term environmental problems. Conclusions on the strength of published findings on crop-environment interactions in maize systems further depend on one’s weighting of economic versus ecological perspectives, physical science versus social science, academic versus grey literature, and quantity versus quality of methods and findings.

EPAR Research Brief #213
Publication Date: 08/31/2013
Type: Literature Review
Abstract

 In this brief we examine the environmental constraints to, and impacts of, smallholder sorghum and millet production systems in Sub-Saharan Africa (SSA) and South Asia (SA). Millet in this paper primarily refers to pearl millet (Pennisetum glaucum), although a number of other millets of significance to smallholder production and food security are also discussed. Sorghum and millets are known for being more tolerant of major environmental stresses including drought and poor soil quality than other major cereals. But water availability is still among the greatest constraints to increased grain production, and soil fertility also significantly limits yields, especially in cases where cultivation occurs on marginal lands and where crop residues are removed for alternative uses. Ultimately sorghum and millets’ relatively higher tolerance to abiotic stresses is expected to promote an increase in global cropping area for sorghum and millets as an adaptation to climate change. Sorghum and millet exhibit relatively few of the environmental impacts commonly associated with more intensively cultivated crops such as fertilizer runoff, pesticide contamination, or water depletion, since both of these crops are overwhelmingly grown by smallholder farmers with few, if any, chemical or irrigation inputs. Nevertheless, the tendency to grow sorghum and millet on marginal and heavily sloped lands does pose some environmental risks – including soil degradation and erosion – that can be mitigated through the adoption of best practices as described in the brief. 

EPAR Technical Report #239
Publication Date: 08/20/2013
Type: Literature Review
Abstract

This research brief provides an overview of the banana and plantain value chains in West Africa. Because of the greater production and consumption of plantains than bananas in the region, the brief focuses on plantains and concentrates on the major plantain-producing countries of Ghana, Cameroon, and Nigeria. The brief is divided into the following sections: Key Statistics (trends in banana and plantain production, consumption, and trade since 1990), Production, Post-Harvest Practices and Challenges, Marketing Systems, and Importance (including household consumption and nutrition). West Africa is one of the major plantain-producing regions of the world, accounting for approximately 32% of worldwide production. Plantains are an important staple crop in the region with a high nutritional content, variety of preparation methods, and a production cycle that is less labor-intensive than many other crops. In addition to plantains, bananas are also grown in West Africa, but they account for only 2.3% of worldwide production. Bananas are more likely than plantains to be grown for export rather than local consumption. Major constraints to banana and plantain production include pests and disease, short shelf life, and damage during transportation.

EPAR Research Brief #216
Publication Date: 08/08/2013
Type: Data Analysis
Abstract

In this brief we analyze patterns of intercropping and differences between intercropped and monocropped plots among smallholder farmers in Tanzania using data from the 2008/2009 wave of the Tanzania National Panel Survey (TZNPS), part of the Living Standards Measurement Study – Integrated Surveys on Agriculture (LSMS-ISA). Intercropping is a planting strategy in which farmers cultivate at least two crops simultaneously on the same plot of land. In this brief we define intercropped plots as those for which respondents answered “yes” to the question “Was cultivation intercropped?” We define “intercropping households” as those households that intercropped at least one plot at any point during the year in comparison to households that did not intercrop any plots. The analysis reveals few significant, consistent productivity benefits to intercropping as currently practiced. Intercropped plots are not systematically more productive (in terms of value produced) than monocropped plots. The most commonly cited reason for intercropping was to provide a substitute crop in the case of crop failure. This suggests that food and income security are primary concerns for smallholder farmers in Tanzania. A separate appendix includes the details for our analyses.

EPAR Technical Report #237
Publication Date: 06/09/2013
Type: Data Analysis
Abstract

Local crop diversity and crop cultivation patterns among smallholder farmers have implications for two important elements of the design of agricultural interventions in developing countries. First, crop cultivation patterns may aid in targeting by helping to identify geographic areas where improved seed and other productivity enhancing technologies will be most easily applicable. Second, these patterns may help to identify potential unintended consequences of crop interventions focused on a single crop (e.g. maize). This report analyzes the distribution of crop diversity and crop cultivation patterns, and factors that can lead to changes in these patterns among smallholder farmers in Tanzania with a focus on regional patterns of crop cultivation and changes in these patterns over time, the factors that affect crop diversity and changes in crop diversity, and the level of substitutability between crops grown by smallholder farmers. All analysis is based on the Tanzania National Panel Survey (TNPS) datasets from 2008 and 2010. The paper is structured as follows. Section I provides a description of regional patterns of crop cultivation and crop diversity between the two years of the panel. Section II presents background on the theoretical factors affecting crop choice, and presents our findings on the results of a multivariate analysis on the factors contributing to crop diversity. Finally, Section 3 provides a preliminary analysis of the level of substitutability between cereal crop of importance in Tanzania (maize, rice and sorghum/millet) and also between these cereal crops and non-cereal crops.

EPAR Technical Report #233
Publication Date: 05/21/2013
Type: Literature Review
Abstract

Whiteflies are vectors for viral diseases such as cassava mosaic disease (CMD) and cassava brown streak disease (CBSD), which can reduce yields substantially. The flies can also cause direct damage, more common on disease-resistant cassava varieties than on local cultivars, by feeding on the crop and causing root yield reductions. In this report we provide background on whitefly damage to cassava as well as evidence on the effectiveness of four control strategies: breeding for host plant resistance, intercropping and other planting strategies, insecticides and Insecticide Resistance Management (IRM), and biological control through parasitoids, fungus, and predators. Though we group information by strategy, most researchers report that controlling whiteflies and the viruses for which it is a vector requires a multifaceted approach. 

EPAR Research Brief #208
Publication Date: 05/01/2013
Type: Literature Review
Abstract

Rice is the most important food crop of the developing world and is grown on over 155 million ha worldwide. Food security of the poor, especially in Asia, depends critically on rice availability at an affordable price. In this brief we examine the environmental constraints to, and impacts of, smallholder rice production systems in South Asia (SA) and Sub-Saharan Africa (SSA), noting where the analysis applies to only one of these regions. We highlight crop-environment interactions at three stages of the rice value chain: pre-production (e.g., land clearing), production (e.g., water and other input use), and post-production (e.g., waste disposal). At each stage we emphasize environmental constraints on production (e.g., poor soil quality, water scarcity, crop pests) and also environmental impacts of crop production (e.g., soil erosion, water depletion, pest resistance). We then highlight best or good practices for minimizing negative environmental impacts in smallholder rice production systems. Evidence on environmental issues in smallholder rice production is uneven. Far more research is available for Asian rice production systems, as compared to African rice systems. And with the possible exception of the evidence on water limits to increasing productivity, conclusions on the strength of published findings on crop-environment interactions in rice depends on one’s weighting of economic versus ecological perspectives, physical science versus social science, academic versus grey literature, and quantity versus quality of methods and findings.