Types of Research
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The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.
We review the current body of literature exploring the theories behind holistic human development measurements and the tradeoffs of different methodologies for the construction of human development indices. Through a systematic review of published and grey literature in the fields of human, international, and economic development we identify 22 current indices that aggregate measures from multiple dimensions of human development. We then analyze these indices to identify tradeoffs related to their unique characteristics and construction methodologies, considering ease of calculation, coverage of different measures of human development, ease of interpretation, comparability, and novelty. The report is accompanied by an appendix of summary tables for each index with further details regarding background information, methodology, index components, and evaluation criteria addressed within the report.
This report provides a summary of findings from six Financial Inclusion Insights (FII) data analysis reports conducted by various agencies for the Bill & Melinda Gates Foundation (BMGF). These reports investigate barriers to financial inclusion and use of digital financial services (DFS) in Bangladesh, India, Kenya, Nigeria, Pakistan, Tanzania, and Uganda. We compile comparable gender-specific statistics, summarize the authors’ findings to determine commonalities and differences across countries, and highlight gender-specific conclusions and recommendations provided in the studies.
The purpose of this literature review is to examine research and decision-making tools that model the impacts of agricultural interventions. We begin with a short explanation of what model features are being described. We then review decision-support tools and user-end modeling tools (menu-driven tools with an interface designed for easy use), as well as academic and professional research models for assessing the potential impacts of agricultural interventions. This review also includes decision tools and models for analyzing agricultural and environmental policies outside of technology impacts in Sub-Saharan Africa and South Asia. The other tools mentioned here, for example a tool that considers nutritional intervention impacts, are included to help provide a broader understanding of the structure and availability of user-end, decision-making tools. In the final section of this brief, we review the most complex models used more in academic research than for in-field decision-making.
Ecosystem services are the benefits people obtain from ecosystems, such as provisioning of fresh water, food, feed, fiber, biodiversity, energy, and nutrient cycling. Agricultural production can substantially affect the functioning of ecosystems, both positively and negatively. The purpose of this report is to provide an overview of the impacts of agricultural technologies and practices on ecosystem services such as soil fertility, water, biodiversity, air, and climate. The report describes the environmental impacts of different aspects of intensive cropping practices and of inputs associated with intensification. We further explore these impacts by examining intensive rice systems and industrial crop processing. Although this report focuses on the impacts of agricultural practices on the environment, many of the practices also have implications for plant, animal, and human health. Farmers and others who come in contact with air, water, and soils polluted by chemical fertilizers and pesticides may face negative health consequences, for instance. By impacting components of the ecosystem, these practices affect the health of plants and animals living within the ecosystem. We find that the unintended environmental consequences of intensive agricultural practices and inputs are varied and potentially severe. In some cases, sustaining or increasing agricultural productivity depends upon reducing impacts to the environment, such as maintaining productive soils by avoiding salinization from irrigation water. However, in other cases, eliminating negative environmental impacts may involve unacceptable trade-offs with food provision or other development goals. Determining the appropriate balance of costs and benefits from intensive agricultural practices is a location-specific exercise requiring knowledge of natural, economic, and social conditions.
Contract farming (CF) is an arrangement between farmers and a processing or marketing firm for the production and supply of agricultural products, often at predetermined prices. This literature review builds on EPAR's review of smallholder contract farming in Sub-Saharan Africa (SSA) and South Asia (EPAR Technical Report #60) by specifically examining the evidence on impacts and potential benefits of contract farming for women in SSA. Key takeaways suggest women’s direct participation in contract farming is limited, with limited access to land and control over the allocation of labor and cash resources key constraints hindering women’s ability to benefit from CF. Further, we find that the impact of contract farming on women is often mediated by their relative bargaining power within the household.
Introducing technology that is designed to be physically appropriate and valuable to women farmers can increase yields and raise income. But gender issues for agricultural technology projects in Sub-Saharan Africa (SSA) are extremely complex. The EPAR series on Gender and Cropping in SSA offers examples of how these issues can affect crop production and adoption of agricultural technologies at each point in the crop cycle for eight crops (cassava, cotton, maize, millet, rice, sorghum, wheat, and yam). This executive summary highlights innovative opportunities for interventions that consider these dimensions of gender. We encourage readers to consult the crop specific briefs for more details. We find that involving both men and women in the development, testing, and dissemination of agricultural technology has been shown to be successful in helping both benefit. Nevertheless, a consistent finding throughout the Gender and Cropping in SSA series is that maximum benefits from technological innovations cannot be realized when upstream factors like education, power, and land tenure heavily influence outcomes. Addressing these more basic upstream causes of gender inequality may be even more important in helping households increase productivity and maximize the benefits of technological interventions.
This research brief reports on full time equivalent (fte) positions devoted to research and development of major food and cash crops in Sub-Saharan Africa (SSA). Data on fte by country and crop were collected from individual Agricultural Science and Technology Indicator (ASTI) country briefs. ASTI data are obtained from unpublished surveys conducted by CGIAR centers. Our report includes 23 countries in SSA.
A widely quoted estimate is that women produce 70 to 80 percent of Sub-Saharan Africa’s (SSA) food. Increasing farmer productivity in SSA therefore requires understanding how these women make planting, harvesting, and other decisions that affect the production, consumption, and marketing of their crops. This brief provides an overview of the gender cropping series highlighting similar themes from the various crops studied, presenting an overarching summary of the findings and conclusion of the individual literature reviews. The studies reviewed suggest that differential preferences and access to assets by men and women can affect adoption levels and the benefits that accrue to men and women. Findings show that women have less secure access to credit, land, inputs, extension, and markets. Similarly, women’s multi-faceted role in household management gives rise to preferences that may very well be different from those of men. Participatory Breeding and Participatory Varietal Selection are two methods shown to be successful in developing technology that is more appropriate and more likely to avoid unintended consequences. Regularly collecting gender-disaggregated statistics can also result in a greater understanding of how technology has affected both men and women. Agricultural technology has the potential to enhance both men’s and women’s welfare and productivity, but unless gender is sufficiently integrated into every step of the development and dissemination process, efforts will only achieve a fraction of their total possible benefit.
Estimates suggest that women grow 70-80 percent of Africa’s food crops, which may constrain their involvement in cash crop production, if food crop production places additional demands their time, resources and labor. There is little evidence regarding women’s motivations or decisions to grow cash versus food crops. Similarly, the policy literature on cotton production and markets in Sub-Saharan Africa (SSA) does not explicitly address the issue of gender, further limiting the information available on the impact of cotton production on women. This brief provides an overview of the role of women in cotton production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that women are typically not the primary cultivators of cotton, and that cotton production is a household cultivation strategy, especially in West and Central Africa. Cotton cultivation often provides access to fertilizers, pesticides and extension services that are otherwise unavailable to households. Women have benefitted from household cotton income when they have input in intra-household resource allocation decisions or when they are able to grow cotton on personal plots and have control over the income it generates. Women also benefit from cotton when it offers them the opportunity to engage in paid labor. The data suggests, however, that cotton cultivation can negatively impact women when it increases their unpaid agricultural labor burden or exposes them to harmful chemicals.