Evans School Policy Analysis & Research Group (EPAR)

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

As part of the Crops & Climate Change series, this brief is presented in three parts: 1) An evaluation of the importance of Sorghum and Millet in SSA, based on production, net exports, and caloric need, 2) A novel analysis of historical and projected climate conditions in Sorghum and Millet growing regions, followed by a summary of the agronomic and physiological vulnerability of Sorghum and Millet crops, 3) A summary of current resources dedicated to sorghum and millet, based on research and development investments and National Adaptation Programmes of Action. Our analysis indicates that sorghum and millets may become increasingly important in those areas of SSA predicted to become hotter and subject to more variable precipitation as a result of climate change. Although sorghum and millet are currently grown on marginal agricultural lands and consumed for subsistence by poorer population segments, climate change could render these drought- and heat-tolerant crops the most viable future cereal production option in some areas where other cereals are currently grown. Fewer international development resources are currently devoted to sorghum and millet than are devoted to other cereal grains, and current resource allocation may not reflect the increased reliance on these grains necessitated by projected climactic changes.

This presentation reviews and presents definitions and theories around incorporating sustainability into agricultural productivity. We review ecological, social, and economic sustainability and examine agricultural productivity through the lenses of nutrition, gender, environment, and climate change. The annotated bibliography identifies critical work from academic literature to aid in defining sustainable agricultural productivity. The methodology to generate these reports included searching the University of Washington Libraries system, Google Scholar, the University of Minnesota’s AgEcon Search, as well as the websites of the FAO, World Bank, and CGIAR. We also reviewed the most recent (2010) publications of the Handbook of Agricultural Economics and the Handbook of Development Economics. 

Agriculture in Sub-Saharan Africa is expected to experience major impacts from climate change, leaving the already food-insecure region subject to the largest contractions of agricultural incomes and food availability. As part of the Crops & Climate Change series, this brief presents an evaluation of the importance of rice in SSA, a novel analysis of historical and projected climate conditions in rice-growing regions in relation to rice's agronomic requirements, and a summary of current resources dedicated to rice. This three-pillared approach serves to identify gaps in resources dedicated to rice productivity in SSA in light of the crop’s resilience to projected changes in climate and increasing importance in the region’s food security. Overall, this analysis indicates that the importance of rice in SSA is increasing even as climate change is projected to have significant effects on the temperature in rice-growing regions. The current resources dedicated to rice research and dissemination of improved methods are insufficient to meet Africa’s rice production needs, and may not reflect the importance of the crop for the region’s food security under the future projected climate.