Types of Research
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The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.
How development organizations, NGOs, and governments can best allocate scarce resources to those in need has long been debated. As opposed to universal allocation of resources, a more targeted approach attempts to minimize program costs while maximizing benefits among those with the greatest need or market opportunity. Drawing on literature from several sectors,this brief presents two categories of beneficiary targeting in the development context: administrative targeting and self-targeting. The paper includes a brief overview of targeting and segmentation in development, a summary of reasons for targeting, theoretical and practical critiques of targeting, and a discussion of targeting methods in research and practice, including examples from the literature. Implementation examples cited in this body of research include food aid program targeting by self-reported household income in Egypt; fertilizer use in low-potential zones of Uganda; and seven strategic initiatives to improve drought and disease resistance in crops in Asia and Sub-Saharan Africa. We find that beneficiary segmentation has several theoretical advantages. Improved targeting may increase the efficiency and equity of organizational and program efforts and help better match interventions to recipient preferences, increasing the likelihood of adoption and participation. Development organizations may improve the focus of both their strategic priorities and budgets through customized targeting methods. However, concerns exist regarding the accuracy, reliability, cost, and time-constraints of targeting methodologies. Creating valid and reliable target groups with implementation potential remains a significant challenge.
Without availability and access to a variety of foods, populations in the developing world are suffering from deficiencies in iron, zinc, iodine, vitamin A, and other micronutrients in addition to deficiencies in energy and protein. Supplementation and fortification programs have demonstrated effectiveness, but there is an increasing interest in potentially more sustainable solutions via agricultural interventions. The review examines the literature regarding agricultural interventions and pathways to diet diversification and whether desired nutritional outcomes are achieved. We find a strong sentiment that agricultural interventions can improve dietary diversity, and that dietary diversity can improve nutrition and related health outcomes. The programs with demonstrated ability to improve nutrition outcomes are most often cross-cutting interventions, borrowing from the agriculture, nutrition, and public health traditions. While these multi-platform programs can be costly to evaluate and difficult to implement, the evidence supports their potential to create sustainable quality-of-life improvements in target regions. The pathways by which agricultural interventions achieve impact are not fully clear, however. The greatest knowledge gaps are directly related to the lack of integration between program design and evaluation. Many evaluations are based on small sample sizes, lack control groups or baseline data, are subject to selection bias, or face other challenges to rigorous statistical analysis.
This report presents data on selected agricultural commodities for the second quarter of 2010 (April through June) and July, August, and September, where available. It provides a summary of recent changes and trends in prices, demand, supply, and market conditions for key agricultural commodities. We find that agricultural commodity prices increased sharply in the second quarter due to an increase in grain prices triggered by supply disruptions in Russia and Eastern Europe. The rise in grain prices led to a rally in commodity prices in August that caused some analysts to question whether markets might return to food price spikes similar to those observed during the 2008 food price crisis. Despite some concerns, however, wheat supplies appear ample and commodity prices seem to have stabilized.
The purpose of this literature review is to examine research and decision-making tools that model the impacts of agricultural interventions. We begin with a short explanation of what model features are being described. We then review decision-support tools and user-end modeling tools (menu-driven tools with an interface designed for easy use), as well as academic and professional research models for assessing the potential impacts of agricultural interventions. This review also includes decision tools and models for analyzing agricultural and environmental policies outside of technology impacts in Sub-Saharan Africa and South Asia. The other tools mentioned here, for example a tool that considers nutritional intervention impacts, are included to help provide a broader understanding of the structure and availability of user-end, decision-making tools. In the final section of this brief, we review the most complex models used more in academic research than for in-field decision-making.
Market-oriented agricultural production can be a mechanism to increase smallholder farmer welfare, rural market performance, and contribute to overall economic growth. Cash crop production can allow households to increase their income by producing output with higher returns to land and labor and using the income generated from sales to purchase goods for consumption. However, in the face of missing and underperforming markets, African smallholder households are often unable to produce efficiently or obtain staple foods reliably and cheaply. This literature review summarizes the available literature on the impact of smallholder participation in cash crop and export markets on household welfare and rural markets. The review focuses exclusively on evidence from Sub-Saharan Africa regarding top and emerging export crops, with the addition of tobacco and horticulture due to the volume of research relevant to smallholder welfare gains from the production of these crops. It includes theoretical frameworks, case studies, empirical evidence, and historical analysis from 42 primary empirical studies and 112 resources overall.
EPAR’s Poultry Markets in West Africa series provides an overview of poultry market trends across West Africa and compares the opportunities for poultry sector development in Benin, Burkina Faso, Côte d’Ivoire, Ghana, Mali, Niger, Nigeria, Senegal and Sierra Leone. The briefs in this series provide detailed country-specific poultry market analyses. The primary resources for these analyses included many reports prepared in response to the avian influenza epidemic, which may explain some of the emphasis on the importance of biosecurity in the available literature. We find that the West African poultry sector faces high production costs, safety concerns due to lack of sanitary controls, and technical constraints in processing and marketing. In addition to biological issues, the lack of breeders, marketing, and processing technology present technical constraints to poultry sector growth.
This report provides an overview of poultry market trends in Benin as compared to the wider West African region. In Benin, live chickens, hens, poultry meat, and eggs for consumption are subject to the 20 percent Common External Tariff (CET), which facilitates an influx of cheap poultry imports from the European Union (EU). Live turkeys and other poultry, reproducers, and hatching eggs are subject to a 5 percent tariff. In the late 1990s, Benin experienced an influx of cheap poultry products primarily from the EU. By 2002, annual poultry imports reached approximately 24,000 tons, more than the poultry imports of any other country in West Africa. In 2004 and 2005, Benin banned imports of poultry and poultry by-products from countries affected by avian influenza. Current information about the poultry industry in Benin is limited. The primary sources for this analysis are a FAO poultry sector review from 2006, a poultry sector project report from the New Partnership for African Development (NEPAD), and a 2006 assessment by the Benin Ministry of Agriculture, Livestock, and Fishing. We find that the poultry sector plays an important economic, social and cultural role in Benin. Poultry and egg production is a major contributor to the agricultural sector and is an important source of nutrition and income for Beninese households. The poultry sector in Benin has the potential to improve the nutritional wellbeing and income security of a large percentage of the population. Traditional smallholders produce the majority of poultry products domestically; however, current production is limited due to low productivity, poor biosecurity, and lack of inputs. We find that a reduction of foreign imports and greater institutional support for the industry may help domestic producers reach their potential.
This report provides an overview of poultry market trends in Sierra Leone as compared to the wider West African region. Sierra Leone did not adopt the Common External Tariff (CET) until 2005, however 2004 tariff rates were already on par with official CET rates. The tariff for live chickens, hens, poultry meat and eggs for consumption remains at 20 percent, which facilitates an influx of cheap poultry imports from Europe. Live turkeys and eggs for hatching are subject to a 5 percent tariff. There is little public information available regarding poultry production in Sierra Leone. The primary sources for this analysis are Government of Sierra Leone documents responding to the avian influenza epidemic in the West African region. This report provides a brief overview of consumption and consumer preferences, domestic production, trade, the political environment, and opportunities for future poultry development in Sierra Leone. Because of the small amount of information regarding poultry production in Sierra Leone, we find that further information is necessary to understand the scope of opportunity for poultry market development.
How development organizations, NGOs, and governments can best allocate scarce resources to those in need has long been debated. As opposed to universal allocation of resources, a more targeted approach attempts to minimize program costs while maximizing benefits among those with the greatest need or market opportunity. Many international development organizations strategically target clients based on geographic location (e.g., community, region, country) or socio-economic indicators, such as the World Bank’s “$1 a day” poverty line. Drawing on literature from several sectors, this brief presents additional methods of beneficiary targeting that international development organizations might consider. We find that beneficiary targeting/segmentation has the potential to make organizational and program efforts more equitable and efficient. With limited resources, smaller organizations have tended to use single robust indicators or simple heuristics, whereas agribusinesses and private sector firms have used more data-intensive marketing tools to position their products. Technological innovation and better access to data have made targeting more prevalent and potentially more affordable in agricultural development. However, creating valid and reliable target segments remains the most significant challenge.