Research Topics

EPAR Technical Report #346
Publication Date: 04/23/2018
Type: Literature Review
Abstract

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

EPAR Research Brief #52
Publication Date: 11/09/2009
Type: Literature Review
Abstract

Ecological farming and conventional farming are two approaches to producing food. The term “ecological farming” describes a range of agricultural systems that seek to provide food and environmental and social benefits by using natural processes and local resources rather than off-farm, purchased inputs (commonly referred to as “external inputs”). Recent debate about the merits of ecological farming over conventional methods has centered on each system’s ability to increase production in the context of numerous and varied biophysical and social constraints. A review of the literature suggests that ecological farming can offer some benefits to smallholder farmers, but that specific approaches must be tailored to local climate and soil conditions and availability of labor, training, and organic inputs.

EPAR Research Brief #75
Publication Date: 11/02/2009
Type: Literature Review
Abstract

In Tanzania, agriculture represents approximately 50 percent of GDP, 80 percent of rural employment, and over 50 percent of the foreign exchange earnings. Yet poor soil fertility and resulting low productivity contribute to low economic growth and widespread poverty. Chemical fertilizer has the potential to contribute to crop yield increases. Yet high prices and weaknesses in the fertilizer market keep fertilizer use low. This literature review examines the history of government interventions that have intended to increase access to fertilizers, and reviews current policies, market structure, and challenges that contribute to the present conditions. We find that despite numerous strategies over the last fifty years, from heavy government involvement to liberalization, major weaknesses in Tanzania’s fertilizer market prevent efficient use of fertilizer. High transportation costs, low knowledge level of farmers and agrodealers, unavailability of improved seed, and limited access to credit all contribute to the market’s problems. The government’s current framework, the Tanzania Agriculture Input Partnership (TAIP), acknowledges this interconnectedness by targeting multiple components of the market. This model could help Tanzania tailor solutions relevant to specific road, soil, and market conditions of different areas of the country, contributing to enhanced food security and economic growth.

EPAR Research Brief #44
Publication Date: 08/17/2009
Type: Literature Review
Abstract

Bt maize technology involves developing hybrid maize crops that incorporate genes from the soil-dwelling bacteria Bacillus thuringiensis (Bt). The primary benefit of Bt maize technology is the heightened crop protection from stem borers, which are maize pests that can inflict serious crop losses. Bt maize has been cultivated in Mexico, South Africa and several countries in the European Union, with limited cultivation in Sub-Saharan Africa (SSA). This report provides a summary of literature on the potential benefits and challenges associated with Bt maize production in SSA. Research studies of Bt maize in the Philippines and South Africa are also briefly reviewed. There is little peer-reviewed literature available, with evidence challenging the assumed benefits of Bt maize for smallholder farmers in SSA. As a result, we also review research briefs and conference proceedings available from reputable international organizations. Although some of the available literature references the ethical concerns over Bt maize production, we focus on searching for science-based discussions related to any potential biodiversity, biosafety, or socio-economic impacts of Bt maize technology for smallholder farmers in SSA.

EPAR Research Brief #79
Publication Date: 07/29/2009
Type: Literature Review
Abstract

The Government of Kenya (GoK) has historically encouraged its farmers to use fertilizer by financing infrastructure and supporting fertilizer markets.  From 1974 to 1984, the GoK provided a fertilizer importation monopoly to one firm, the Kenya Farmers Association.  However, the GoK saw that this monopoly impeded fertilizer market development by prohibiting competing firms from entering the market and, in the latter half of the 1980s, encouraged other firms to enter the highly regulated fertilizer market. This report examines the state of fertilizer use in Kenya by reviewing and summarizing literature on recent fertilizer price increases, Kenya’s fertilizer usage trends and approaches, market forces, and the impact of government and non-government programs. We find that most studies of Kenya’s fertilizer market find it to be well functioning and generally competitive, and conclude that market reform has stimulated fertilizer use mainly by improving farmers’ access to the input through the expansion of private retail networks. Overall fertilizer consumption in Kenya has increased steadily since 1980, and fertilizer use among smallholders is among the highest in Sub-Saharan Africa. Yet fertilizer consumption is still limited, especially on cereal crops, and in areas where agroecological conditions create greater risks and lower returns to fertilizer use.

EPAR Research Brief #32
Publication Date: 06/30/2009
Type: Literature Review
Abstract

Though not indigenous to Sub-Saharan Africa (SSA), cassava plays, to varying degrees, five major roles in African development: famine-reserve crop, rural food staple, cash crop for urban consumption, livestock feed, and industrial raw material. Cassava production in SSA was historically a significant staple crop for smallholder farmers and continues to be the second most important food crop in Africa (after maize) in terms of calories consumed. Subsistence crops such as cassava are often considered women’s crops with the standard explanation that women are responsible for feeding the family and thus prefer to grow crops for the household. This brief reviews the role that women play in cassava production, and considers ways to better address gender issues from planting through post-harvest production. We find that the potential gains to cassava production made possible through improved technology will not be fully realized without the participation of women farmers and without women farmers having access to credit, markets, and extension services. Additionally, evidence from SSA suggests that labor for harvesting and processing, rather than labor for weeding, has become the key labor constraint for cassava, and addressing this concern may be more important than further yield increases for raising production levels.

EPAR Technical Report #35
Publication Date: 05/13/2009
Type: Literature Review
Abstract

This report provides a general overview of trends in public and private agricultural research and development (R&D) funding and expenditures in Sub-Saharan Africa (SSA). The request is divided into two sections, covering public funding and private funding. Within each section, relevant data is presented on historical funding patterns, the types of research conducted, and which countries within SSA are financing R&D at the highest level. We find that the majority of growth in African public agricultural research funding took place in the 1960s, when real public spending on agricultural research increased 6% a year. From 1971 to 2000 annual growth averaged 1.4% a year. Public financing of agricultural R&D experienced a moderate shift in the 1990s from bilateral and multilateral donor funding to domestic government financing. The shift varied by country, but donor funding dropped for all SSA countries an average of 10%. Private research and development funding is heavily concentrated in developed countries with the United States and Japan the two biggest spenders. Within SSA, private R&D expenditures comprise 2% of all R&D spending. The main private actors in SSA are companies based in South Africa and Nigeria. The private sector is focused on research areas that involve marketable inputs, such as chemicals, seeds, and machines/

EPAR Research Brief #27
Publication Date: 05/09/2009
Type: Literature Review
Abstract

As a source of employment for over 20 million Sub-Saharan African (SSA) farmers and the fastest-growing food source in Africa, rice plays a vital role in African economies and daily life. Women play a substantial role in SSA rice production and rely heavily on the income it generates. Not recognizing this role has often resulted in development and research projects failing to address women’s well-being and also failing to achieve project and development goals. Female farmers in SSA have been less likely than male farmers to adopt productivity-enhancing rice technologies such as improved seeds, fertilizer, pesticides, or small machinery, even when those technologies are designed specifically to help women. A more complete understanding of the dynamics and diversity of gender roles in rice farming is necessary to improve the likelihood of successful interventions. This brief provides an overview of the role of women in rice production, and provides a framework for analyzing technology’s impact on women throughout the cropping cycle. We find that labor constraints, low education levels, cultural inappropriateness, and asymmetric access to resources all contribute to low adoption of rice technology by women. In order to fully realize the poverty reduction benefits of increased rice production in SSA, evidence suggests that research and extension programs must consider how interventions will affect women along every stage of the production chain. The effect on women and their households will vary depending on region, culture, ethnicity, socio-economic status, and role in cultivating rice.

EPAR Technical Report #34
Publication Date: 05/03/2009
Type: Literature Review
Abstract

Lack of nitrogen (N) is often cited as the most limiting factor in agriculture. Although N composes nearly 80% of the atmosphere, plants are unable to use this form of the element (N2) because of the strong triple bonds between the two atoms. Nitrogen deficiency is especially problematic in the soils of Sub-Saharan Africa (SSA). Low levels of N and other soil fertility problems have severe poverty, malnutrition and environmental degradation consequences for SSA. The process by which atmospheric N2 is converted into N compounds that can be used by living things is called nitrogen fixation. Biological nitrogen fixation (BNF or biofixation) offers an alternative or additional means to traditional nitrogen fixation to increase plant-available nitrogen. Through a symbiotic relationship, an N-fixing bacterium infects a plant (usually a legume) and forms nodules on the roots of the plant in which N fixation occurs. This literature review examines the expansion and benefits of BNF, the constraints to BNF adoption, BNF regulations, and success stories of developing and distributing BNF technologies worldwide. BNF technology can be an efficient and effective tool for decreasing environmental degradation and increasing soil fertility, yields, income, and food security in SSA, although many constraints to farmer adoption exist. 

EPAR Technical Report #18
Publication Date: 04/15/2009
Type: Literature Review
Abstract

This report present a thorough review of relevant literature regarding labor constraints currently being faced in Sub-Saharan Africa (SSA).  The review focuses on the impacts of labor supply issues, particularly as they relate to the use of new technology and management techniques, off farm labor migration, and the impacts of HIV/AIDS. The review is provides a basic breakdown of the different kinds of agricultural labor in SSA, before presenting the evidence on the causes and impact of agricultural labor constraints. Though labor constraints can be relevant on both the demand and supply side, especially for certain groups such as women and youth, our review follows the literature by focusing on the supply side issues. The literature reviewed was written between 1990 and 2008, and includes a combination of reports from government organizations and highly cited journal articles.