Types of Research
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The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.
This poster presentation summarizes research on changes in crop planting decisions on the extensive and intensive margin in Tanzania, with regards to changes in agricultural land that a farmer has available and area planted in the context of smallholders and farming systems. We use household survey data from the Tanzania National Panel Survey (TNPS), part of the World Bank’s Living Standards Measurement Study–Integrated Surveys on Agriculture (LSMS – ISA) to test how much the agricultural land available to households changes, how much farmers change the proportion of land decidated to growing priority crops, and how crop area changes vary with changes in landholding. We find that almost half of households had a change of agricultural land area of at least half a hectare from 2008-2010. Smallholder farmers on average decreased the amount of available land between 2008 and 2010, while non-smallholder farmers increased agricultural land area during that time period, but that smallholder households planted a greater proportion of their agricultural land than nonsmallholders. Eighty percent of households changed crop proportions from 2008 to 2010, yet aggregate level indicators mask household level changes.
The commercial alcohol industry in Africa may provide opportunities to increase market access and incomes for smallholder farmers by increasing access to agriculture-alcohol value chains. Despite the benefits of increased market opportunities, the high costs to human health and social welfare from increased alcohol use and alcoholism could contribute to a net loss for society. To better understand the tradeoffs between increased market access for smallholders and societal costs associated with harmful alcohol consumption, this paper provides an inventory of the societal costs of alcohol in Sub-Saharan Africa (SSA). We examine direct costs associated with addressing harmful effects of alcohol and treating alcohol-related illnesses, as well as indirect costs associated with the goods and services that are not delivered as a consequence of drinking and its impact on personal productivity. We identified resources using Google Scholar and the University of Washington libraries, and utilized the Global Burden of Disease (GBD) database by the Institute for Health Metrics and Evaluation (IHME) and the World Health Organization’s Global Information System on Alcohol and Health (GISAH) database. We also utilized FAOSTAT to retrieve raw data on national-level alcohol production and export statistics. We find that hazardous alcohol use contributes to early mortality and morbidity, loss of productivity, property damage, and other social costs and harms for drinkers and those around them. Drinking also affects vulnerable segments of the population disproportionately. Policymakers, local authorities, and donor agencies can use the information presented in this paper to plan and prepare for the higher consumption levels and subsequent social costs that may follow through agricultural development and economic growth in the region.
The purpose of this analysis is to provide a measure of marketable surplus of maize in Tanzania. We proxy marketable surplus with national-level estimates of total maize sold, presumably the surplus for maize producing and consuming households. We also provide national level estimates of total maize produced and estimate “average prices” for Tanzania which allows this quantity to be expressed as an estimate of the value of marketable surplus. The analysis uses the Tanzanian National Panel Survey (TNPS) LSMS – ISA which is a nationally representative panel survey, for the years 2008/2009 and 2010/2011. A spreadsheet provides our estimates for different subsets of the sample and using different approaches to data cleaning and weighting. The total number of households for Tanzania was estimated with linear extrapolation based on the Tanzanian National Bureau of Statistics for the years 2002 and 2012. The weighted proportions of maize-producing and maize-selling households were multiplied to the national estimate of total households. This estimate of total Tanzanian maize-selling and maize-producing households was then multiplied by the average amount sold and by the average amount produced respectively to obtain national level estimates of total maize sold and total maize produced in 2009 and 2011.