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EPAR Technical Report #346
Publication Date: 04/23/2018
Type: Literature Review
Abstract

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

EPAR Technical Report #200
Publication Date: 08/24/2012
Type: Literature Review
Abstract

This report investigates the potential environmental and socio-economic benefits and costs of glyphosate resistant cassava.  Glyphosate resistant crops (also referred to as glyphosate tolerant) have been rapidly adopted by a number of crop producers because they simplify and/or reduce the cost of weed management. Glyphosate resistant crops also provide external environmental benefits by promoting reduced tillage agriculture, decreasing erosion and increasing soil health. However, glyphosate resistant crops also have some environmental costs, potentially leading to increased use of herbicides and environmental contamination. Because transgenic glyphosate resistant cassava is not currently in use, literature on its potential environmental and socioeconomic costs and benefits is limited. Therefore, this report draws on the literature for glyphosate resistant crops that are in current use, including maize, soybeans, sugar beets and canola (rapeseed). We find that socioeconomic and environmental impacts of glyphosate resistant crops differ by crop-type, agroecological conditions, production systems and local regulatory structure. Therefore, some benefits and costs associated with other glyphosate resistant crops may not be applicable to glyphosate resistant cassava. 

EPAR Technical Report #184
Publication Date: 07/11/2012
Type:
Abstract

This brief provides an overview of the national and zonal characteristics of agricultural production in Tanzania using the 2008/2009 wave of the Tanzania National Panel Survey (TZNPS), part of the Living Standards Measurement Study – Integrated Surveys on Agriculture (LSMS-ISA). More detailed information and analysis is available in the separate EPAR Tanzania LSMS-ISA Reference Report, Sections A-G.

EPAR Research Brief #190
Publication Date: 03/30/2012
Type: Data Analysis
Abstract

This brief presents a comparative analysis of men and women and of male- and female-headed households in Tanzania using data from the 2008/2009 wave of the Tanzania National Panel Survey (TZNPS), part of the Living Standards Measurement Study – Integrated Surveys on Agriculture (LSMS-ISA). We compare farm activity, productivity, input use, and sales as well as labor allocations by gender of the respondent and of the household head. In households designated “female-headed” a woman was the decision maker in the household, took part in the economy, control and welfare of the household, and was recognized by others in the household as the head. For questions regarding household labor (both non-farm and farm), the gender of the individual laborer is recorded, and we use this to illustrate the responsibilities of male and female household members. An appendix provides the details for our analyses.