Research Topics

EPAR Technical Report #346
Publication Date: 04/23/2018
Type: Literature Review
Abstract

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

EPAR Research Brief #360
Publication Date: 02/05/2018
Type: Research Brief
Abstract

In this brief, we report on measures of economic growth, poverty and agricultural activity in Ethiopia. For each category of measure, we first describe different measurement approaches and present available time series data on selected indicators. We then use data from the sources listed below to discuss associations within and between these categories between 1994 and 2017. 

EPAR Research Brief #316
Publication Date: 12/13/2015
Type: Literature Review
Abstract

The literature on poverty’s causes and cures in developing countries posits a variety of contributing factors. Most researchers acknowledge that a sustained exit from poverty is complex and no single causal pathway from poverty to non-poverty exists. In this review, we present a summary framework for categorizing the various theorized pathways out of poverty, and evaluate the empirical evidence for which interventions and resulting outcomes are most frequently and most strongly associated with poverty alleviation. We conducted a literature review on pathways out of poverty for low-income households in developing countries and identified and categorized general strategies and outcomes demonstrated to be empirically associated with poverty alleviation. We organized the general strategies into four asset groups that could be targeted to alleviate poverty: human, natural, built / financial, and social / political. Much of the literature presents positive results on poverty alleviation, but it is difficult to compare across studies because many of the studies were conducted in different countries and at different scales, and use a variety of outcome measures.

EPAR Technical Report #306
Publication Date: 09/18/2015
Type: Literature Review
Abstract

We review the status and characteristics of 48 national identity programs and initiatives in 43 developing countries, and evaluate how these programs are being connected to—or used for—service provision. The identity programs we review are mainly government-issued national IDs. However, we also review other types of national identity programs with links to various services including voter cards, passports, and two programs targeting the poor and the banking population. Following a brief review of the roles of identity systems in development and recent identity system trends, we present an overview of the 48 national identity programs, including technical features (such as whether physical identities incorporate an electronic component or are embedded with biometric features), implementation status, population enrollment strategies, and coverage. We next review evidence of implementation challenges around accountability, privacy, data management, enrollment, coverage, cost, and harmonization of identity programs. Finally, we present the functional applications of national identity programs, reporting how these programs are linked with services in finance, health, agriculture, elections, and other areas, and analyzing whether particular identity program characteristics are associated with functional applications.

EPAR Technical Report #311
Publication Date: 08/06/2015
Type: Literature Review
Abstract

This report provides a summary of findings from six Financial Inclusion Insights (FII) data analysis reports conducted by various agencies for the Bill & Melinda Gates Foundation (BMGF). These reports investigate barriers to financial inclusion and use of digital financial services (DFS) in Bangladesh, India, Kenya, Nigeria, Pakistan, Tanzania, and Uganda. We compile comparable gender-specific statistics, summarize the authors’ findings to determine commonalities and differences across countries, and highlight gender-specific conclusions and recommendations provided in the studies. 

EPAR Research Brief #312
Publication Date: 07/30/2015
Type: Literature Review
Abstract

This brief reviews the evidence of realized yield gains by smallholder farmers attributable to the use of high-quality seed and/or improved seed varieties. Our analysis suggests that in most cases, use of improved varieties and/or quality seed is associated with modest yield increases.  In the sample of 395 trials reviewed, positive yield changes accompanied the use of improved variety or quality seed, on average, in 10 out of 12 crops, with rice and cassava as the two exceptions.

EPAR Technical Report #293
Publication Date: 03/31/2015
Type: Literature Review
Abstract

This report reviews the current body of peer-reviewed scholarship exploring the impacts of morbidity on economic growth. This overview seeks to provide a concise introduction to the major theories and empirical evidence linking morbidity – and the myriad different measures of morbidity – to economic growth, which is defined primarily in terms of gross domestic product (GDP) and related metrics (wages, productivity, etc.). Through a systematic review of published manuscripts in the fields of health economics and economic development we further identify the most commonly-used pathways linking morbidity to economic growth. We also highlight the apparent gaps in the empirical literature (i.e., theorized pathways from morbidity to growth that remain relatively untested in the published empirical literature to date).

EPAR Research Brief #44
Publication Date: 08/17/2009
Type: Literature Review
Abstract

Bt maize technology involves developing hybrid maize crops that incorporate genes from the soil-dwelling bacteria Bacillus thuringiensis (Bt). The primary benefit of Bt maize technology is the heightened crop protection from stem borers, which are maize pests that can inflict serious crop losses. Bt maize has been cultivated in Mexico, South Africa and several countries in the European Union, with limited cultivation in Sub-Saharan Africa (SSA). This report provides a summary of literature on the potential benefits and challenges associated with Bt maize production in SSA. Research studies of Bt maize in the Philippines and South Africa are also briefly reviewed. There is little peer-reviewed literature available, with evidence challenging the assumed benefits of Bt maize for smallholder farmers in SSA. As a result, we also review research briefs and conference proceedings available from reputable international organizations. Although some of the available literature references the ethical concerns over Bt maize production, we focus on searching for science-based discussions related to any potential biodiversity, biosafety, or socio-economic impacts of Bt maize technology for smallholder farmers in SSA.

EPAR Research Brief #51
Publication Date: 07/02/2009
Type: Research Brief
Abstract

Yam is a major staple in West and Central Africa and an important supplementary food in East Africa. In Sub-Saharan Africa (SSA), virtually all yams are produced for human consumption, with women responsible for processing yams for consumption. This brief provides an overview of the role of women in yam production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that though yam was traditionally considered a man’s crop, it is clear that women farmers contribute greatly to yam cultivation, especially during weeding, harvesting, and processing. Propagation of improved varieties with resistance to pests and diseases like yam mosaic disease has great potential to benefit women farmers. Increased yields and lower post-harvest losses will increase household food security.  However, because yams extract high amounts of nutrients from the soil, soil and land management techniques are necessary to ensure future gains in yield. Women’s groups serve as potential venues for dissemination of new yam cultivation and processing technologies.  Additionally, women’s groups can undertake new propagation techniques as income generating activities.  Women farmers need increased extension efforts to fully benefit from technology improvements.

EPAR Research Brief #40
Publication Date: 06/29/2009
Type: Research Brief
Abstract

The millets, a group of small-seeded grasses indigenous to Africa, are an extremely important staple food in resource-poor regions of Sub-Saharan Africa (SSA). Millet requires few inputs, suffers less from insect pests and disease than other grains,  and can tolerate areas even too hot and dry for sorghum.  These characteristics make millet an essential component of food security and risk management strategies for many Africans, though both consumption and production per capita of millet has declined in the last 20 years as farmers have shifted toward maize and rice production. This brief provides an overview of the role of women in millet production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that the shift away from millet may result in poorer nutrition and increased time burden for women where they must find alternatives to millet fuel, but that little is known about these consequences. Investing in improved varieties that account for both men’s and women’s preferences, introducing labor-saving technology, and increasing market access all have the potential to increase millet’s production and consumption on the continent.