Evans School Policy Analysis & Research Group (EPAR)

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

This report provides a general overview of the wheat market in Bangladesh. The first section describes trends in wheat production and consumption over the past twenty years and summarizes recent trade policy related to wheat. The second section presents the findings of a literature review of the wheat value chain in Bangladesh, beginning with seed selection and ending with sales. Finally, wheat consumption in Bangladesh is discussed in more depth, including nutritional information about wheat, substitute grain markets, and projected consumption in 2030. We find that wheat production in Bangladesh has been volatile and continues to reflect significant yield gaps. While wheat consumption has increased, rice is the most important crop and food grain. Increased demand by private traders for higher quality wheat for processing has fueled rising import levels, and the the gap between domestic supply and demand is projected to grow to over 4 million tons by 2030.

This brief provides a general overview of the wheat market in Bihar, in India. The first section describes trends in wheat production and consumption over the past twenty years and summarizes recent trade policy related to wheat. After a brief discussion of the types and nutritional content of wheat, the third section describes the wheat value chain in Bihar, beginning with seed development and ending with marketing. Finally, we highlight a few trends in Bihar wheat markets. We find that the quantity of wheat production in Bihar has exceeded rice production over the past four years, and that in the last two decades, wheat consumption has grown significantly among both urban and rural populations. Climate change and deteriorating land quality, however, may threaten agricultural production in Bihar in the long-term.

Agriculture and Climate Change: Part I

With estimated global emissions of 5,969-6,615 metric tons (Mt) of carbon dioxide (CO2) per year, agriculture accounts for about 13.5% of total global anthropogenic emissions of greenhouse gases (GHG). Deforestation contributes about 11.8% of total GHG emissions, releasing about 5,800 Mt CO2 per year. Developing countries are largely responsible for emissions from agriculture and deforestation, with the developing countries of South Asia and East Asia accounting for 17% and 25% of global agricultural emissions respectively. Sub-Saharan Africa (SSA) accounts for about 13% of global emissions from agriculture and 15% of emissions from land use change and forestry. This report examines the biophysical and economic potential of mitigating agriculture and land use GHG emissions, and provides a summary on the current and projected impact of global carbon market mechanisms on emission reductions. 

Agriculture and Climate Change: Part II

This report covers two topics related to agriculture and climate change in developing countries. The first section discusses the role of agricultural offsets in mitigating greenhouse gas emissions. Recent negotiations around a post-Kyoto Protocol agreement have included debate about whether agricultural carbon sequestration projects should be eligible under the Clean Development Mechanism (CDM). We examine the reasons for supporting or opposing this type of CDM reform and how these reasons relate to impacts on development goals and smallholder farmers, scientific uncertainty about carbon sequestration, and philosophical disagreement about the use of emission offsets. The second section covers proposed agricultural adaptation activities in Africa and other developing countries. While the majority of developing countries have outlined immediate adaptation needs in National Adaptation Programs of Action (NAPAs), few have made progress in implementing adaptation activities. We find that issues related to financial resources, scientific and technical information, and capacity building continue to challenge developing countries in preparing for the impacts of climate change.