Research Topics

EPAR Technical Report #346
Publication Date: 04/23/2018
Type: Literature Review
Abstract

The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.

EPAR Presentation #280
Publication Date: 08/12/2014
Type: Data Analysis
Abstract

This poster presentation summarizes research on changes in crop planting decisions on the extensive and intensive margin in Tanzania, with regards to changes in agricultural land that a farmer has available and area planted in the context of smallholders and farming systems. We use household survey data from the Tanzania National Panel Survey (TNPS), part of the World Bank’s Living Standards Measurement Study–Integrated Surveys on Agriculture (LSMS – ISA) to test how much the agricultural land available to households changes, how much farmers change the proportion of land decidated to growing priority crops, and how crop area changes vary with changes in landholding. We find that almost half of households had a change of agricultural land area of at least half a hectare from 2008-2010. Smallholder farmers on average decreased the amount of available land between 2008 and 2010, while non-smallholder farmers increased agricultural land area during that time period, but that smallholder households planted a greater proportion of their agricultural land than nonsmallholders. Eighty percent of households changed crop proportions from 2008 to 2010, yet aggregate level indicators mask household level changes.