Types of Research
The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.
We review the current body of literature exploring the theories behind holistic human development measurements and the tradeoffs of different methodologies for the construction of human development indices. Through a systematic review of published and grey literature in the fields of human, international, and economic development we identify 22 current indices that aggregate measures from multiple dimensions of human development. We then analyze these indices to identify tradeoffs related to their unique characteristics and construction methodologies, considering ease of calculation, coverage of different measures of human development, ease of interpretation, comparability, and novelty. The report is accompanied by an appendix of summary tables for each index with further details regarding background information, methodology, index components, and evaluation criteria addressed within the report.
Yam is a major staple in West and Central Africa and an important supplementary food in East Africa. In Sub-Saharan Africa (SSA), virtually all yams are produced for human consumption, with women responsible for processing yams for consumption. This brief provides an overview of the role of women in yam production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that though yam was traditionally considered a man’s crop, it is clear that women farmers contribute greatly to yam cultivation, especially during weeding, harvesting, and processing. Propagation of improved varieties with resistance to pests and diseases like yam mosaic disease has great potential to benefit women farmers. Increased yields and lower post-harvest losses will increase household food security. However, because yams extract high amounts of nutrients from the soil, soil and land management techniques are necessary to ensure future gains in yield. Women’s groups serve as potential venues for dissemination of new yam cultivation and processing technologies. Additionally, women’s groups can undertake new propagation techniques as income generating activities. Women farmers need increased extension efforts to fully benefit from technology improvements.
Though not indigenous to Sub-Saharan Africa (SSA), cassava plays, to varying degrees, five major roles in African development: famine-reserve crop, rural food staple, cash crop for urban consumption, livestock feed, and industrial raw material. Cassava production in SSA was historically a significant staple crop for smallholder farmers and continues to be the second most important food crop in Africa (after maize) in terms of calories consumed. Subsistence crops such as cassava are often considered women’s crops with the standard explanation that women are responsible for feeding the family and thus prefer to grow crops for the household. This brief reviews the role that women play in cassava production, and considers ways to better address gender issues from planting through post-harvest production. We find that the potential gains to cassava production made possible through improved technology will not be fully realized without the participation of women farmers and without women farmers having access to credit, markets, and extension services. Additionally, evidence from SSA suggests that labor for harvesting and processing, rather than labor for weeding, has become the key labor constraint for cassava, and addressing this concern may be more important than further yield increases for raising production levels.
The millets, a group of small-seeded grasses indigenous to Africa, are an extremely important staple food in resource-poor regions of Sub-Saharan Africa (SSA). Millet requires few inputs, suffers less from insect pests and disease than other grains, and can tolerate areas even too hot and dry for sorghum. These characteristics make millet an essential component of food security and risk management strategies for many Africans, though both consumption and production per capita of millet has declined in the last 20 years as farmers have shifted toward maize and rice production. This brief provides an overview of the role of women in millet production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that the shift away from millet may result in poorer nutrition and increased time burden for women where they must find alternatives to millet fuel, but that little is known about these consequences. Investing in improved varieties that account for both men’s and women’s preferences, introducing labor-saving technology, and increasing market access all have the potential to increase millet’s production and consumption on the continent.
Sorghum grows well in arid and semi-arid agroecological zones and is thus one of the most important cereals in the Sahel region of Sub-Saharan Africa (SSA). Both men and women cultivate sorghum primarily for household consumption, though women are nearly exclusively responsible for post-harvest production of the grain, including brewing and selling sorghum beer. This brief provides an overview of the role of women in sorghum production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that improved sorghum varieties have the potential to greatly increase sorghum yields in SSA by alleviating cultivation threats from striga, pests, and drought. Because women farmers are the primary cultivators of sorghum, they stand to benefit most from these improved varieties. However, low adoption rates of new technologies suggest that more resources need to be dedicated to extension efforts and informal seed distribution networks that include women farmers. Post-harvest processing of sorghum is both time and labor intensive and is causing many women farmers to transition to maize or rice. Finally, increased demand for sorghum as a biofuel stock may not translate into gains for women farmers as expected, because women farmers tend to lack input resources, and women farmers often lose control over crops as they transition to cash crops.
In Sub-Saharan Africa (SSA), maize alone provides an estimated one third of the mean caloric intake and in 2006, accounted for 21% of all harvested food crops, making it the single most important food crop in the region. In addition, maize is also used as feedgrain and fodder, adding to its importance in integrated smallholder farming systems in SSA. In general, women are the main producers of staple crops such as maize. Understanding the gender dimensions of maize is particularly challenging because maize is used as both a subsistence and cash crop, and may be considered either a male or female crop depending on farmer circumstances and how the particular variety is promoted. This brief provides an overview of the role of women in maize production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that lower access to factors such as extension access, education level, land, and labor contribute to female’s lower rate of maize technology adoption. Understanding women’s disproportionate access to resources and how improved technology may change allocation of resources should help project developers improve both women’s and men’s productivity.
In the last half century, the increased opportunity cost of women’s time in Sub-Saharan Africa (SSA) has led to remarkable growth in the consumption of wheat and other easy-to-prepare staples. Wheat tends to be grown and processed on a large scale in SSA. Ethiopia (SSA’s largest producer of wheat) is the exception, where smallholders are responsible for 76% of total production. This brief provides an overview of the role of women in wheat production, and provides a framework for analyzing technology’s impact on women throughout the cropping cycle. We find that many constraints exist to adoption of improved wheat varieties by women. A review of improved wheat variety adoption in the developing world found that it takes 5-10 years after breeding to the release and another 5-10 years for full adoption, but this length of time has been found to be reduced with the use of participatory breeding, varietal selection, and gender analysis. By including women in every stage of development and planning of new technologies, programs can become more aware of the needs of targeted women and therefore, increase adoption rates and improve the productivity of men and women in wheat farming.
This report provides a general overview of trends in public and private agricultural research and development (R&D) funding and expenditures in Sub-Saharan Africa (SSA). The request is divided into two sections, covering public funding and private funding. Within each section, relevant data is presented on historical funding patterns, the types of research conducted, and which countries within SSA are financing R&D at the highest level. We find that the majority of growth in African public agricultural research funding took place in the 1960s, when real public spending on agricultural research increased 6% a year. From 1971 to 2000 annual growth averaged 1.4% a year. Public financing of agricultural R&D experienced a moderate shift in the 1990s from bilateral and multilateral donor funding to domestic government financing. The shift varied by country, but donor funding dropped for all SSA countries an average of 10%. Private research and development funding is heavily concentrated in developed countries with the United States and Japan the two biggest spenders. Within SSA, private R&D expenditures comprise 2% of all R&D spending. The main private actors in SSA are companies based in South Africa and Nigeria. The private sector is focused on research areas that involve marketable inputs, such as chemicals, seeds, and machines/
As a source of employment for over 20 million Sub-Saharan African (SSA) farmers and the fastest-growing food source in Africa, rice plays a vital role in African economies and daily life. Women play a substantial role in SSA rice production and rely heavily on the income it generates. Not recognizing this role has often resulted in development and research projects failing to address women’s well-being and also failing to achieve project and development goals. Female farmers in SSA have been less likely than male farmers to adopt productivity-enhancing rice technologies such as improved seeds, fertilizer, pesticides, or small machinery, even when those technologies are designed specifically to help women. A more complete understanding of the dynamics and diversity of gender roles in rice farming is necessary to improve the likelihood of successful interventions. This brief provides an overview of the role of women in rice production, and provides a framework for analyzing technology’s impact on women throughout the cropping cycle. We find that labor constraints, low education levels, cultural inappropriateness, and asymmetric access to resources all contribute to low adoption of rice technology by women. In order to fully realize the poverty reduction benefits of increased rice production in SSA, evidence suggests that research and extension programs must consider how interventions will affect women along every stage of the production chain. The effect on women and their households will vary depending on region, culture, ethnicity, socio-economic status, and role in cultivating rice.