Types of Research
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The private sector is the primary investor in health research and development (R&D) worldwide, with investment annual investment exceeding $150 billion, although only an estimated $5.9 billion is focused on diseases that primarily affect low and middle-income countries (LMICs) (West et al., 2017b). Pharmaceutical companies are the largest source of private spending on global health R&D focused on LMICs, providing $5.6 billion of the $5.9 billion in total private global health R&D per year. This report draws on 10-K forms filed by Pharmaceutical companies with the U.S. Securities and Exchange Commission (SEC) in the year 2016 to examine the evidence for five specific disincentives to private sector investment in drugs, vaccines and therapeutics for global health R&D: scientific uncertainty, weak policy environments, limited revenues and market uncertainty, high fixed costs for research and manufacturing, and imperfect markets. 10-K reports follow a standard format, including a business section and a risk section which include information on financial performance, investment options, lines of research, promising acquisitions and risk factors (scientific, market, and regulatory). As a result, these filings provide a valuable source of information for analyzing how private companies discuss risks and challenges as well as opportunities associated with global health R&D targeting LMICs.
In this brief we analyze patterns of intercropping and differences between intercropped and monocropped plots among smallholder farmers in Tanzania using data from the 2008/2009 wave of the Tanzania National Panel Survey (TZNPS), part of the Living Standards Measurement Study – Integrated Surveys on Agriculture (LSMS-ISA). Intercropping is a planting strategy in which farmers cultivate at least two crops simultaneously on the same plot of land. In this brief we define intercropped plots as those for which respondents answered “yes” to the question “Was cultivation intercropped?” We define “intercropping households” as those households that intercropped at least one plot at any point during the year in comparison to households that did not intercrop any plots. The analysis reveals few significant, consistent productivity benefits to intercropping as currently practiced. Intercropped plots are not systematically more productive (in terms of value produced) than monocropped plots. The most commonly cited reason for intercropping was to provide a substitute crop in the case of crop failure. This suggests that food and income security are primary concerns for smallholder farmers in Tanzania. A separate appendix includes the details for our analyses.
The following brief details the various policies surrounding donor agency salary supplementation (or top-up) to individuals employed in project countries. The goal of this research was to understand the landscape of different agency’s policies regarding salary top-ups for government experts and scientists advising on donor projects. However, information on this specific scenario was limited. The brief covers a range of scenarios in which donor agencies may pay salary top-ups to local, in-country individuals and aims to draw out a number of hypothesized advantages and disadvantages associated with the practice of donor salary supplementation.
This paper is the third in EPAR’s series on Higher Education in Africa. Our research tasks in this phase build on Phase I, in which we sought to identify measurable rates of return on tertiary agricultural education in Africa and describe the current state of African higher agricultural education (HAE), and Phase II, in which we identified countries’ experiences with national higher education capacity building through partnership building, cross-border opportunities such as ‘twinning,’ and various retention and diaspora engagement strategies. In this phase we discuss successful regional education models, particularly in Sub-Saharan Africa. We have organized our findings and analysis into three sections.The first section organizes the literature under categories of regional higher education models or ‘hubs’ and discusses measurement of the regional impact of higher education. The second section provides bibliometric data identifying academically productive countries and universities in Sub-Saharan Africa.The final section provides a list of regional higher education models identified in the literature and through a web-based review of existing higher education networks and hubs. We also include a list of challenges and responses to regional coordination.
On July 10, 2009 at the Italy G8 summit, attendees issued a joint statement pledging to contribute $20 billion towards agricultural development and food security in the developing world over the next three years. This research brief notes the status of the contributions made to the L’Aquila Food Security Initiative and whether any of the $20 billion will be allocated to agricultural research. We conclude that no declarations have been made as of September 2009 on how much of the $20 billion will be allocated to agricultural research, and which types of research will be funded by the initiative.
Yam is a major staple in West and Central Africa and an important supplementary food in East Africa. In Sub-Saharan Africa (SSA), virtually all yams are produced for human consumption, with women responsible for processing yams for consumption. This brief provides an overview of the role of women in yam production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that though yam was traditionally considered a man’s crop, it is clear that women farmers contribute greatly to yam cultivation, especially during weeding, harvesting, and processing. Propagation of improved varieties with resistance to pests and diseases like yam mosaic disease has great potential to benefit women farmers. Increased yields and lower post-harvest losses will increase household food security. However, because yams extract high amounts of nutrients from the soil, soil and land management techniques are necessary to ensure future gains in yield. Women’s groups serve as potential venues for dissemination of new yam cultivation and processing technologies. Additionally, women’s groups can undertake new propagation techniques as income generating activities. Women farmers need increased extension efforts to fully benefit from technology improvements.
Though not indigenous to Sub-Saharan Africa (SSA), cassava plays, to varying degrees, five major roles in African development: famine-reserve crop, rural food staple, cash crop for urban consumption, livestock feed, and industrial raw material. Cassava production in SSA was historically a significant staple crop for smallholder farmers and continues to be the second most important food crop in Africa (after maize) in terms of calories consumed. Subsistence crops such as cassava are often considered women’s crops with the standard explanation that women are responsible for feeding the family and thus prefer to grow crops for the household. This brief reviews the role that women play in cassava production, and considers ways to better address gender issues from planting through post-harvest production. We find that the potential gains to cassava production made possible through improved technology will not be fully realized without the participation of women farmers and without women farmers having access to credit, markets, and extension services. Additionally, evidence from SSA suggests that labor for harvesting and processing, rather than labor for weeding, has become the key labor constraint for cassava, and addressing this concern may be more important than further yield increases for raising production levels.
The millets, a group of small-seeded grasses indigenous to Africa, are an extremely important staple food in resource-poor regions of Sub-Saharan Africa (SSA). Millet requires few inputs, suffers less from insect pests and disease than other grains, and can tolerate areas even too hot and dry for sorghum. These characteristics make millet an essential component of food security and risk management strategies for many Africans, though both consumption and production per capita of millet has declined in the last 20 years as farmers have shifted toward maize and rice production. This brief provides an overview of the role of women in millet production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that the shift away from millet may result in poorer nutrition and increased time burden for women where they must find alternatives to millet fuel, but that little is known about these consequences. Investing in improved varieties that account for both men’s and women’s preferences, introducing labor-saving technology, and increasing market access all have the potential to increase millet’s production and consumption on the continent.
Sorghum grows well in arid and semi-arid agroecological zones and is thus one of the most important cereals in the Sahel region of Sub-Saharan Africa (SSA). Both men and women cultivate sorghum primarily for household consumption, though women are nearly exclusively responsible for post-harvest production of the grain, including brewing and selling sorghum beer. This brief provides an overview of the role of women in sorghum production, and provides a framework for analyzing barriers to women and technology’s impact on women throughout the cropping cycle. We find that improved sorghum varieties have the potential to greatly increase sorghum yields in SSA by alleviating cultivation threats from striga, pests, and drought. Because women farmers are the primary cultivators of sorghum, they stand to benefit most from these improved varieties. However, low adoption rates of new technologies suggest that more resources need to be dedicated to extension efforts and informal seed distribution networks that include women farmers. Post-harvest processing of sorghum is both time and labor intensive and is causing many women farmers to transition to maize or rice. Finally, increased demand for sorghum as a biofuel stock may not translate into gains for women farmers as expected, because women farmers tend to lack input resources, and women farmers often lose control over crops as they transition to cash crops.